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Headquarters, Costa Importantly, HHLA2 is independent of PD-L1 and is often most strongly expressed in PD-L1-negative cancers. An investment decision regarding the securities referred to herein should only NextPoint Therapeutics Announces $80 Million Series B Financing co-led Sustainable Development Goals, Position prohibited or restricted. the Bayer press portal. I understand that it may affect my rights. As part of the financing, Rakhshita Dhar, Senior Director of Venture Investments Health at Leaps by Bayer, and Paulina Hill, Partner at Sanofi Ventures, will join the NextPoint Board of Directors. Our innovative approach integrates foundational science with a defined clinical biomarker to deliver a new class of monotherapies for patients who will not benefit from PD-1/L1 inhibitors. PLEASE READ THIS DOCUMENT CAREFULLY BEFORE YOU ACCESS OR USE THE WEBSITE OR CONTENT. Bayer is committed to driving sustainable development and generating a positive impact with its businesses. +49 214 30 1, Mllerstrae 178 Pharmacists, - NextPoint Therapeutics, a Cambridge, Mass.-based immuno-oncology development company, raised $80 million in Series B funding. There will be no public Detlev Biniszkiewicz, Ph.D. - MPM Capital We may also use web beacons or pixels, and in certain circumstances may collect IP address, screen resolution and browser software and operating system types, clickstream patterns, dates and times that our site is accessed, and other categories of data. NextPoint Therapeutics is an exciting early-stage Boston-area startup company working at the frontier of immuno-oncology. Sanofi Ventures is the corporate venture capital arm of Sanofi. interstate or foreign commerce, or of any facility of a national securities exchange of the United 10-01-2023 Print. Nutrition The financing will be used to advance NextPoint . land, water and energy. To learn more, visit nextpointtx.com. Team, Our We have no control over, do not review, and are not responsible for Third-Party Sites, their content, or any goods or services available through the Third-Party Sites. NextPoint Therapeutics is an exciting early-stage Boston-area startup company working at the frontier of immuno-oncology. Hub Langenfeld, Accelerate In some cases where we are not already authorized to process the Personal Data under applicable law, we may ask for your consent to process your Personal Data: We may disclose Personal Data as described in this Privacy Notice, including: We may create de-identified or anonymous data from Personal Data by removing data components (such as your name, email address, or linkable tracking ID) that make the data personally identifiable to you or through obfuscation or through other means. The company offers to build a broad strategic pipeline of first-in-class immunotherapies based on a novel, validated checkpoint axis, expanding the potential of immunotherapy. Stock Market | sweetwaterreporter.com | Sweetwater Reporter Leaps by Bayer and Sanofi Ventures co-led the round and were joined . NextPoint is building a deep understanding of the HHLA2 tumor-specific immune-escape mechanism, with the ultimate goal of establishing standalone treatments in cancers with high HHLA2 expression, said Detlev Biniszkiewicz, PhD, Chief Executive Officer of NextPoint Therapeutics. Trends, Rise Governance, Sustainability relied upon in connection with, any offer or commitment whatsoever in any jurisdiction. The company offers immunotherapies for a validated checkpoint axis that is independent of PD-1/L1 and modulates both adaptive and innate immune systems to find and destroy cancer cells. . Our Privacy Notice does not apply to Third-Party Sites. 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If you would like to stop receiving newsletters or other marketing or promotional messages, notifications, or updates, you may do so by following the unsubscribe instructions that appear in these e-mail communications. Last Name First Name Middle Name; Biniszkiewicz: Detlev: Street Address 1 Street Address 2; Sanofi Ventures invests in early-stage biotech and digital health companies with innovative ideas and transformative new products and technologies of strategic interest to Sanofi. Cambridge, MA / Leverkusen, Germany January 10, 2023 NextPoint Therapeutics, a biotechnology company developing a new world of precision immuno-oncology, announced today that it raised $80 million in Series B financing co-led by Leaps by Bayer, the impact investment arm of Bayer AG, and Sanofi Ventures, the strategic venture capital arm for Sanofi. 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Further, it does not constitute a The company and its founders have shown in preclinical models and with analysis of existing clinical datasets that the HHLA2 pathway is an important tumor-suppressive mechanism in many patients, NextPoint is advancing the field of immuno-oncology through its leading scientific work on the novel HHLA2 pathway. jurisdictions, only certain categories of person may be allowed to view such materials. 50 This announcement is an advertisement and does not, under any circumstances, constitute a public We are currently looking to add an Associate Director or Director, Clinical Operations to our fast moving, roll-up your sleeves team environment. Please note that if you are visiting the Site from outside of the United States, your information may be transferred to, stored, and/or processed in the US. 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To analyze and improve our Services, administer our Site and Services, provide you with access to our Services, analyze and improve our information technology, monitor compliance with our Terms of Use, and enforce our Terms of Use or other legal or regulatory obligations. Detlev is a serial entrepreneur and an experienced biopharma executive who brings deep knowledge of oncology and immuno-oncology to his role. our employees, International Use, Privacy Leena Gandhi, MD, PhD, was named chief medical officer of NextPoint Therapeutics, a biotechnology company focused on immuno-oncology through its work on the HHLA2 pathway. Vote, Voting NextPoint originated from the combined expertise of its academic founders, Gordon Freeman, PhD, of the Dana-Farber Cancer Institute, and XingXing Zang, PhD, of Albert Einstein College of Medicine. You can use the Easy Apply feature on LinkedIn view job description. News, Conditions of With our distinctive knowledge of people, animals and plants, we focus on the areas of health care and nutrition. NextPoint Therapeutics Announces $80 Million Series B Financing co-led by Leaps by Bayer and Sanofi Ventures to Advance Novel Immuno-Oncology Programs Programs target the novel HHLA2 pathway, activating anti-tumor immune responses to find and destroy cancer cells Cookies can remember login information, preferences, and similar information. Council, Stakeholder 2+ years experience managing direct reports including oversight of CRAs. Previous study start-up and clinical monitoring experience desired. Oricell Therapeutics was founded in 2015 as an innovative biopharmaceutical company in China. China, United NextPoint Therapeutics, a biotechnology company developing a new world of precision immuno-oncology, announced today that it raised $80 million in Series B financing co-led by Leaps by Bayer, the impact investment arm of Bayer AG, and Sanofi Ventures, the strategic venture capital arm for Sanofi.. NextPoint Therapeutics is an exciting early-stage Boston-area startup company working at the frontier of immuno-oncology. Our team of proven drug developers is working closely with our renowned scientific founders to launch a new world of precision immuno-oncology. Germany Copyright and Legal Notice. Leena is a proven leader in immuno-oncology and a brilliant physician-scientist, and our team will benefit greatly from her academic and drug development expertise as NextPoint moves forward in its next stage of growth, said Detlev Biniszkiewicz, PhD, Chief Executive Officer of NextPoint Therapeutics. Cambridge, MA / Leverkusen, Germany, January 10, 2023 NextPoint Therapeutics, a biotechnology company developing a new world of precision immuno-oncology, announced today that it raised $80 million in Series B financing co-led by Leaps by Bayer, the impact investment arm of Bayer AG, and Sanofi Ventures, the strategic venture capital arm for Sanofi. Jan 10, 2023. www.precisiononcologynews.com . Postings, Latest Worldwide, News & Some cookies and other technologies may serve to track Personal Data previously entered by a web user on our site. any facility of a national securities exchange of the United States and the tender offer cannot be 2021 Feb;9(2):156-169. NextPoint Therapeutics, a biotechnology company developing a new world of precision immuno-oncology, announced today the appointment of Leena Gandhi, MD, PhD, as Chief Medical Officer (CMO).. As CMO, Dr. Gandhi will oversee the clinical development of NextPoint's precision immuno-oncology programs that target the newly discovered HHLA2 pathway to activate anti-tumor immune responses. Our use or disclosure of de-identified or anonymized data is not subject to this Privacy Notice. on & Medical Devices, Crop to apply, The Our team of proven drug developers is working closely with our renowned scientific founders to launch a new world of precision immuno-oncology. About NextPoint Therapeutics. The Bayer brand stands for trust, reliability and quality throughout the world. 2021 Jul 9;6(61):9792. Any person who is not a relevant person should not act or rely on the 14 new chief medical officers in February Clin Cancer Res. Contact Information Website www.nextpointtx.com Ownership Status Privately Held (backing) Financing Status Venture Capital-Backed Primary Industry Drug Discovery Independently design, execute and manage translational research activities from discovery through clinical development, Develop and implement research and clinical-level assays, along with data analysis, interpretation, and report generation, Work closely with the research and preclinical team to identify novel biomarkers and translate to the clinical setting, Integrate biomarker and clinical data to guide patient stratification, Manage CROs responsible for the generation of both exploratory and clinical biomarker data, Contribute to clinical documents such as, INDs, IBs, regulatory submissions, laboratory manuals and clinical protocols, Function as a scientific thought leader inside the company for cutting edge biomarker approaches. This announcement does not contain or constitute an offer of, Leaps by Bayer and Sanofi Ventures led the round for the Cambridge, Massachusetts-based company. We are thrilled to support NextPoint, an exciting addition to our oncology portfolio, as it works to redefine the treatment landscape of immuno-oncology.. Conduct, Product Tuesday's. We will also retain your Personal Data as necessary to comply with our legal obligations, resolve disputes, and enforce our agreements. Innovations, Redefining public offer of the securities in the United States. Leena Gandhi, director of the Dana-Farber Cancer Institute's Center for Cancer Therapeutic Innovation and a 15-year veteran of the organization, has left to become chief medical officer of. While immune checkpoint inhibitors targeting PD-1/L1 have revolutionized cancer treatments,. NextPoint Therapeutics, Inc. Street Address 1 Street Address 2; 238 MAIN STREET: City State/Province/Country ZIP/PostalCode Phone Number of Issuer; CAMBRIDGE: MASSACHUSETTS: 02142: 5082041115: 3. The Site provides a venue to obtain information about NextPoint, our activities, and products we may offer. Gandhi is departing the Dana-Farber Institute to become chief medical officer at NextPoint Therapeutics, a private Boston-area biotech with backing from MPM, Bayer and Sanofi. Prospectus Directive. jurisdiction. Reporting to the Chief Medical Officer, the Clinical Operations Lead will help define strategy and lead launch, execution, and oversight of early phase clinical trials. We also use cookies and similar technologies for purposes of marketing and advertising. One of the candidates, lademirsen, is in a phase 2 trial for the treatment of Alport Syndrome. Results, AGM NextPoint is building a deep understanding of the HHLA2 tumor-specific immune-escape mechanism, with the ultimate goal of establishing standalone treatments in cancers with high HHLA2 expression, said Detlev Biniszkiewicz, PhD, Chief Executive Officer of NextPoint Therapeutics. Counterfeits, Recognizing The securities referred to herein will not be registered under the U.S. Securities Act of 1933, as R&D expenses before special items amounted to 5.3 billion euros. Contact Us - Nextpoint About NextPoint Therapeutics Founded by MPM Capital, NextPoint Therapeutics, Inc. has assembled a team of proven drug developers to build a broad strategic pipeline of first-in-class immunotherapies with the goal of delivering new options to people with cancer. Dialogue, UN Global NextPoint Therapeutics Appoints Leena Gandhi, MD, PhD, as Chief Medical search, Main The above described license is conditioned on your compliance with these Terms, and shall terminate upon termination of these Terms. NextPoint Therapeutics, a biotechnology company developing a new world of precision immuno-oncology, announced today the appointment of Leena Gandhi, MD, PhD, as Chief Medical Officer (CMO).. As CMO, Dr. Gandhi will oversee the clinical development of NextPoint's precision immuno-oncology programs that target the newly discovered HHLA2 pathway to activate anti-tumor immune responses. KIR3DL3-HHLA2 is a human immunosuppressive pathway and a therapeutic target. Our innovative approach integrates foundational science with a defined clinical biomarker to deliver a new class of monotherapies for patients who will not benefit from PD-1/L1 inhibitors. NextPoint does not sell your Personal Information. Please note that the Site does not alter its behavior or use practices when we receive a Do Not Track signal from your browser. Stock Market | Finance As part of the financing, Rakhshita Dhar, Senior Director of Venture Investments Health at Leaps by Bayer, and Paulina Hill, Partner at Sanofi Ventures, will join the NextPoint Board of Directors. Existing investors that took part in the financing include MPM Capital Management, Dana-Farber Cancer Institutes Binney Street Capital and NextPoint founder Gordon Freeman, PhD. NextPoint Therapeutics Raises $80M in Series B Financing | Precision Oncology News The firm plans to put the funds toward its investigational immunotherapies targeting HHLA2 on difficult-to-treat, PD-L1-negative cancers. CAMBRIDGE, Mass. The tender offer referenced herein is not being made, directly or Phone: +49 30 468 1111, Alfred-Nobel-Str. The Bayer brand stands for trust, reliability and quality throughout the world. 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